Periconception onset diabetes is associated with embryopathy and fetal growth retardation, reproductive tract hyperglycosylation and impaired immune adaptation to pregnancy

Diabetes has been linked with impaired fertility but the underlying mechanisms are not well defined. Here we use a streptozotocin-induced diabetes mouse model to investigate the cellular and biochemical changes in conceptus and maternal tissues that accompany hyperglycaemia. We report that streptozo...

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Detalles Bibliográficos
Autores principales: Brown, Hannah M., Green, Ella S., Tan, Tiffany C. Y., Gonzalez, Macarena B., Rumbold, Alice R., Hull, M. Louise, Norman, Robert J., Packer, Nicolle H., Robertson, Sarah A., Thompson, Jeremy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794861/
https://www.ncbi.nlm.nih.gov/pubmed/29391475
http://dx.doi.org/10.1038/s41598-018-19263-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794861/
https://www.ncbi.nlm.nih.gov/pubmed/29391475
http://dx.doi.org/10.1038/s41598-018-19263-8

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