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Oral delivery of siRNA lipid nanoparticles: Fate in the GI tract

Oral delivery, a patient-friendly means of drug delivery, is preferred for local administration of intestinal therapeutics. Lipidoid nanoparticles, which have been previously shown to deliver siRNA to intestinal epithelial cells, have potential to treat intestinal disease. It is unknown, however, wh...

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Detalles Bibliográficos
Autores principales: Ball, Rebecca L., Bajaj, Palak, Whitehead, Kathryn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794865/
https://www.ncbi.nlm.nih.gov/pubmed/29391566
http://dx.doi.org/10.1038/s41598-018-20632-6