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Oral delivery of siRNA lipid nanoparticles: Fate in the GI tract
Oral delivery, a patient-friendly means of drug delivery, is preferred for local administration of intestinal therapeutics. Lipidoid nanoparticles, which have been previously shown to deliver siRNA to intestinal epithelial cells, have potential to treat intestinal disease. It is unknown, however, wh...
Autores principales: | Ball, Rebecca L., Bajaj, Palak, Whitehead, Kathryn A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794865/ https://www.ncbi.nlm.nih.gov/pubmed/29391566 http://dx.doi.org/10.1038/s41598-018-20632-6 |
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