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The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders

Major mood disorders, which primarily include bipolar disorder and major depressive disorder, are the leading cause of disability worldwide and pose a major challenge in identifying robust risk genes. Here, we present data from independent large-scale clinical data sets (including 29 557 cases and 3...

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Detalles Bibliográficos
Autores principales: Chang, H, Hoshina, N, Zhang, C, Ma, Y, Cao, H, Wang, Y, Wu, D-d, Bergen, S E, Landén, M, Hultman, C M, Preisig, M, Kutalik, Z, Castelao, E, Grigoroiu-Serbanescu, M, Forstner, A J, Strohmaier, J, Hecker, J, Schulze, T G, Müller-Myhsok, B, Reif, A, Mitchell, P B, Martin, N G, Schofield, P R, Cichon, S, Nöthen, M M, Walter, H, Erk, S, Heinz, A, Amin, N, van Duijn, C M, Meyer-Lindenberg, A, Tost, H, Xiao, X, Yamamoto, T, Rietschel, M, Li, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794872/
https://www.ncbi.nlm.nih.gov/pubmed/28070120
http://dx.doi.org/10.1038/mp.2016.231