JNK1 controls adult hippocampal neurogenesis and imposes cell-autonomous control of anxiety behaviour from the neurogenic niche

Promoting adult hippocampal neurogenesis is expected to induce neuroplastic changes that improve mood and alleviate anxiety. However, the underlying mechanisms remain largely unknown and the hypothesis itself is controversial. Here we show that mice lacking Jnk1, or c-Jun N-terminal kinase (JNK) inh...

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Detalles Bibliográficos
Autores principales: Mohammad, H, Marchisella, F, Ortega-Martinez, S, Hollos, P, Eerola, K, Komulainen, E, Kulesskaya, N, Freemantle, E, Fagerholm, V, Savontous, E, Rauvala, H, Peterson, B D, van Praag, H, Coffey, E T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794884/
https://www.ncbi.nlm.nih.gov/pubmed/27843149
http://dx.doi.org/10.1038/mp.2016.203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794884/
https://www.ncbi.nlm.nih.gov/pubmed/27843149
http://dx.doi.org/10.1038/mp.2016.203

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