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Changed gene expression in subjects with schizophrenia and low cortical muscarinic M1 receptors predicts disrupted upstream pathways interacting with that receptor

We tested the hypothesis that, compared with subjects with no history of psychiatric illness (controls), changes in gene expression in the dorsolateral prefrontal cortex from two subgroups of subjects with schizophrenia, one with a marked deficit in muscarinic M1 receptors (muscarinic receptor-defic...

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Detalles Bibliográficos
Autores principales: Scarr, E, Udawela, M, Thomas, E A, Dean, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794886/
https://www.ncbi.nlm.nih.gov/pubmed/27801890
http://dx.doi.org/10.1038/mp.2016.195