OTTO: a new strategy to extract mental disease-relevant combinations of GWAS hits from individuals

Despite high heritability of schizophrenia, genome-wide association studies (GWAS) have not yet revealed distinct combinations of single-nucleotide polymorphisms (SNPs), relevant for mental disease-related, quantifiable behavioral phenotypes. Here we propose an individual-based model to use genome-w...

Descripción completa

Detalles Bibliográficos
Autores principales: Ehrenreich, H, Mitjans, M, Van der Auwera, S, Centeno, T P, Begemann, M, Grabe, H J, Bonn, S, Nave, K-A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794905/
https://www.ncbi.nlm.nih.gov/pubmed/27922606
http://dx.doi.org/10.1038/mp.2016.208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794905/
https://www.ncbi.nlm.nih.gov/pubmed/27922606
http://dx.doi.org/10.1038/mp.2016.208

Ejemplares similares