Link between the causative genes of holoprosencephaly: Zic2 directly regulates Tgif1 expression

One of the causal genes for holoprosencephaly (HPE) is ZIC2 (HPE5). It belongs to the zinc finger protein of the cerebellum (Zic) family of genes that share a C2H2-type zinc finger domain, similar to the GLI family of genes. In order to clarify the role of Zic2 in gene regulation, we searched for it...

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Detalles Bibliográficos
Autores principales: Ishiguro, Akira, Hatayama, Minoru, Otsuka, Maky I., Aruga, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794963/
https://www.ncbi.nlm.nih.gov/pubmed/29391420
http://dx.doi.org/10.1038/s41598-018-20242-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794963/
https://www.ncbi.nlm.nih.gov/pubmed/29391420
http://dx.doi.org/10.1038/s41598-018-20242-2

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