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Link between the causative genes of holoprosencephaly: Zic2 directly regulates Tgif1 expression
One of the causal genes for holoprosencephaly (HPE) is ZIC2 (HPE5). It belongs to the zinc finger protein of the cerebellum (Zic) family of genes that share a C2H2-type zinc finger domain, similar to the GLI family of genes. In order to clarify the role of Zic2 in gene regulation, we searched for it...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794963/ https://www.ncbi.nlm.nih.gov/pubmed/29391420 http://dx.doi.org/10.1038/s41598-018-20242-2 |