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The Molecular Basis of the Sodium Dodecyl Sulfate Effect on Human Ubiquitin Structure: A Molecular Dynamics Simulation Study

To investigate the molecular interactions of sodium dodecyl sulfate (SDS) with human ubiquitin and its unfolding mechanisms, a comparative study was conducted on the interactions of the protein in the presence and absence of SDS at different temperatures using six independent 500 ns atomistic molecu...

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Detalles Bibliográficos
Autores principales: Jafari, Majid, Mehrnejad, Faramarz, Rahimi, Fereshteh, Asghari, S. Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794983/
https://www.ncbi.nlm.nih.gov/pubmed/29391595
http://dx.doi.org/10.1038/s41598-018-20669-7