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Diverse patterns of molecular changes in the mechano-responsiveness of focal adhesions

Focal adhesions anchor contractile actin fibers with the extracellular matrix, sense the generated tension and respond to it by changing their morphology and composition. Here we ask how this mechanosensing is enabled at the protein-network level, given the modular assembly and multitasking of focal...

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Detalles Bibliográficos
Autores principales: Malik-Sheriff, Rahuman S., Imtiaz, Sarah, Grecco, Hernán E., Zamir, Eli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795008/
https://www.ncbi.nlm.nih.gov/pubmed/29391434
http://dx.doi.org/10.1038/s41598-018-20252-0