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Seeding of proteins into amyloid structures by metabolite assemblies may clarify certain unexplained epidemiological associations

The accumulation of various metabolites appears to be associated with diverse human diseases. However, the aetiological link between metabolic alteration and the observed diseases is still elusive. This includes the correlation between the abnormally high levels of homocysteine and quinolinic acid i...

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Detalles Bibliográficos
Autores principales: Sade, Dorin, Shaham-Niv, Shira, Arnon, Zohar A., Tavassoly, Omid, Gazit, Ehud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795054/
https://www.ncbi.nlm.nih.gov/pubmed/29367352
http://dx.doi.org/10.1098/rsob.170229