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PINK1 import regulation; a fine system to convey mitochondrial stress to the cytosol
Insights from inherited forms of parkinsonism suggest that insufficient mitophagy may be one etiology of the disease. PINK1/Parkin-dependent mitophagy, which helps maintain a healthy mitochondrial network, is initiated by activation of the PINK1 kinase specifically on damaged mitochondria. Recent in...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795276/ https://www.ncbi.nlm.nih.gov/pubmed/29325568 http://dx.doi.org/10.1186/s12915-017-0470-7 |