Involvement of hedgehog pathway in early onset, aggressive molecular subtypes and metastatic potential of breast cancer

BACKGROUND: Dysregulation of hedgehog pathway is observed in numerous cancers. Relevance of hedgehog pathway genes in cancer cohort and inhibition of its downstream effector (GLI1) towards metastasis in cell lines are explored in the study. METHOD: One hundred fifty fresh tumours of breast cancer pa...

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Detalles Bibliográficos
Autores principales: Riaz, Syeda Kiran, Khan, Jahangir Sarwar, Shah, Syed Tahir Abbas, Wang, Fen, Ye, Lin, Jiang, Wen G., Malik, Muhammad Faraz Arshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795292/
https://www.ncbi.nlm.nih.gov/pubmed/29329585
http://dx.doi.org/10.1186/s12964-017-0213-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795292/
https://www.ncbi.nlm.nih.gov/pubmed/29329585
http://dx.doi.org/10.1186/s12964-017-0213-y

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