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Genotyping of KRAS Mutational Status by the In-Check Lab-on-Chip Platform

The KRAS oncogene is involved in the pathogenesis of several types of cancer, particularly colorectal cancer (CRC). The most frequent mutations in this gene are associated with poor survival, increased tumor aggressiveness and resistance to therapy with anti-epidermal growth factor receptor (EGFR) a...

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Detalles Bibliográficos
Autores principales: Guarnaccia, Maria, Iemmolo, Rosario, San Biagio, Floriana, Alessi, Enrico, Cavallaro, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795341/
https://www.ncbi.nlm.nih.gov/pubmed/29304017
http://dx.doi.org/10.3390/s18010131