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microRNA-4331 Promotes Transmissible Gastroenteritis Virus (TGEV)-induced Mitochondrial Damage Via Targeting RB1, Upregulating Interleukin-1 Receptor Accessory Protein (IL1RAP), and Activating p38 MAPK Pathway In Vitro

Transmissible gastroenteritis virus (TGEV), a member of the coronaviridae family, could cause fatal diarrhea of piglets and result in numerous economic losses. Previous studies demonstrated that TGEV infection could lead to mitochondrial damage and upregulate miR-4331 level. So miR-4331 may play an...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaomin, Bai, Xiaoyuan, Guan, Lijuan, Li, Juejun, Song, Xiangjun, Ma, Xuelian, Guo, Jianxiong, Zhang, Zhichao, Du, Qian, Huang, Yong, Tong, Dewen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795386/
https://www.ncbi.nlm.nih.gov/pubmed/29217619
http://dx.doi.org/10.1074/mcp.RA117.000432