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The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes

Mitochondria exert an immense amount of cytophysiological functions, but the structural basis of most of these processes is still poorly understood. Here we use cross-linking mass spectrometry to probe the organization of proteins in native mouse heart mitochondria. Our approach provides the largest...

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Detalles Bibliográficos
Autores principales: Liu, Fan, Lössl, Philip, Rabbitts, Beverley M., Balaban, Robert S., Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795388/
https://www.ncbi.nlm.nih.gov/pubmed/29222160
http://dx.doi.org/10.1074/mcp.RA117.000470