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Compartment-resolved Proteomic Analysis of Mouse Aorta during Atherosclerotic Plaque Formation Reveals Osteoclast-specific Protein Expression

Atherosclerosis leads to vascular lesions that involve major rearrangements of the vascular proteome, especially of the extracellular matrix (ECM). Using single aortas from ApoE knock out mice, we quantified formation of plaques by single-run, high-resolution mass spectrometry (MS)-based proteomics....

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Detalles Bibliográficos
Autores principales: Wierer, Michael, Prestel, Matthias, Schiller, Herbert B., Yan, Guangyao, Schaab, Christoph, Azghandi, Sepiede, Werner, Julia, Kessler, Thorsten, Malik, Rainer, Murgia, Marta, Aherrahrou, Zouhair, Schunkert, Heribert, Dichgans, Martin, Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795394/
https://www.ncbi.nlm.nih.gov/pubmed/29208753
http://dx.doi.org/10.1074/mcp.RA117.000315