The Abrogation of Phosphorylation Plays a Relevant Role in the CCR5 Signalosome Formation with Natural Antibodies to CCR5

The exposure to CCR5 (CC chemokine receptor 5) specific natural antibodies in vitro produces a Class B β-arrestin2-dependent CCR5 retention with the aid of ERK1, due to the formation of a CCR5 signalosome, which remains stable for at least 48 h. Considering that β-arrestins and MAPKs are receptive t...

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Detalles Bibliográficos
Autores principales: Venuti, Assunta, Pastori, Claudia, Siracusano, Gabriel, Pennisi, Rosamaria, Riva, Agostino, Tommasino, Massimo, Sciortino, Maria Teresa, Lopalco, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795422/
https://www.ncbi.nlm.nih.gov/pubmed/29283386
http://dx.doi.org/10.3390/v10010009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795422/
https://www.ncbi.nlm.nih.gov/pubmed/29283386
http://dx.doi.org/10.3390/v10010009

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