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Sustained IFN-I Expression during Established Persistent Viral Infection: A “Bad Seed” for Protective Immunity
Type I interferons (IFN-I) are one of the primary immune defenses against viruses. Similar to all other molecular mechanisms that are central to eliciting protective immune responses, IFN-I expression is subject to homeostatic controls that regulate cytokine levels upon clearing the infection. Howev...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795425/ https://www.ncbi.nlm.nih.gov/pubmed/29301196 http://dx.doi.org/10.3390/v10010012 |