E3L and F1L Gene Functions Modulate the Protective Capacity of Modified Vaccinia Virus Ankara Immunization in Murine Model of Human Smallpox

The highly attenuated Modified Vaccinia virus Ankara (MVA) lacks most of the known vaccinia virus (VACV) virulence and immune evasion genes. Today MVA can serve as a safety-tested next-generation smallpox vaccine. Yet, we still need to learn about regulatory gene functions preserved in the MVA genom...

Descripción completa

Detalles Bibliográficos
Autores principales: Volz, Asisa, Jany, Sylvia, Freudenstein, Astrid, Lantermann, Markus, Ludwig, Holger, Sutter, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795434/
https://www.ncbi.nlm.nih.gov/pubmed/29300297
http://dx.doi.org/10.3390/v10010021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795434/
https://www.ncbi.nlm.nih.gov/pubmed/29300297
http://dx.doi.org/10.3390/v10010021

Ejemplares similares