A Built-In CpG Adjuvant in RSV F Protein DNA Vaccine Drives a Th1 Polarized and Enhanced Protective Immune Response

Human respiratory syncytial virus (RSV) is the most significant cause of acute lower respiratory infection in children. However, there is no licensed vaccine available. Here, we investigated the effect of five or 20 copies of C-Class of CpG ODN (CpG-C) motif incorporated into a plasmid DNA vaccine e...

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Detalles Bibliográficos
Autores principales: Ma, Yao, Jiao, Yue-Ying, Yu, Yun-Zhou, Jiang, Nan, Hua, Ying, Zhang, Xiu-Juan, Fu, Yuan-Hui, Peng, Xiang-Lei, Zheng, Yan-Peng, Anderson, Larry J., He, Jin-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795451/
https://www.ncbi.nlm.nih.gov/pubmed/29342954
http://dx.doi.org/10.3390/v10010038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795451/
https://www.ncbi.nlm.nih.gov/pubmed/29342954
http://dx.doi.org/10.3390/v10010038

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