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Metformin protects against oxidized low density lipoprotein-induced macrophage apoptosis and inhibits lipid uptake

Oxidized low density lipoprotein (ox-LDL)-induced macrophage apoptosis contributes to the formation of atherosclerosis. Metformin, an antidiabetic drug, has been reported to attenuate lipid accumulation in macrophages. In this study, the effects of metformin on ox-LDL-induced macrophage apoptosis we...

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Detalles Bibliográficos
Autores principales: Huangfu, Ning, Wang, Yong, Cheng, Jingsong, Xu, Zhenyu, Wang, Shenghuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795518/
https://www.ncbi.nlm.nih.gov/pubmed/29456653
http://dx.doi.org/10.3892/etm.2018.5704