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Carbenoxolone inhibits mechanical stress-induced osteogenic differentiation of mesenchymal stem cells by regulating p38 MAPK phosphorylation

The aim of the present study was to explore the effects of pannexin1 (Px1) protein channels on osteogenic differentiation of mesenchymal stem cells (MSCs) under mechanical stress stimulation. MSCs were isolated from Sprague Dawley rats (3 weeks old, weighing 100–120 g) and cultured in vitro. A safe...

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Detalles Bibliográficos
Autores principales: Li, Shenglong, Wang, Jing, Han, Yudi, Li, Xiaoteng, Liu, Changjian, Lv, Zhengshuai, Wang, Xiuhui, Tang, Xin, Wang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795701/
https://www.ncbi.nlm.nih.gov/pubmed/29456683
http://dx.doi.org/10.3892/etm.2018.5757