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Keeping it real: MRX–Sae2 clipping of natural substrates
The yeast Mre11–Rad50–Xrs2 (MRX) complex and Sae2 function together to initiate DNA end resection, an essential early step in homology-dependent repair of DNA double-strand breaks (DSBs). In this issue of Genes & Development, Wang and colleagues (pp. 2331–2336) and Reginato and colleagues (pp. 2...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795777/ https://www.ncbi.nlm.nih.gov/pubmed/29352017 http://dx.doi.org/10.1101/gad.310771.117 |