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Oncohistones: drivers of pediatric cancers

One of the most striking results in the area of chromatin and cancer in recent years has been the identification of recurrent mutations in histone genes in pediatric cancers. These mutations occur at high frequency and lead to the expression of mutant histones that exhibit oncogenic features. Thus,...

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Detalles Bibliográficos
Autores principales: Mohammad, Faizaan, Helin, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795778/
https://www.ncbi.nlm.nih.gov/pubmed/29352018
http://dx.doi.org/10.1101/gad.309013.117