Cargando…

Afadin and RhoA control pancreatic endocrine mass via lumen morphogenesis

Proper lumen morphogenesis during pancreas development is critical to endocrine and exocrine cell fate. Recent studies showed that a central network of lumens (termed core), but not the surrounding terminal branches (termed periphery), produces most islet endocrine cells. To date, it remains unclear...

Descripción completa

Detalles Bibliográficos
Autores principales: Azizoglu, D. Berfin, Braitsch, Caitlin, Marciano, Denise K., Cleaver, Ondine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795784/
https://www.ncbi.nlm.nih.gov/pubmed/29330353
http://dx.doi.org/10.1101/gad.307637.117