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Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing

Initiation of eukaryotic chromosome replication follows a spatiotemporal program. The current model suggests that replication origins compete for a limited pool of initiation factors. However, it remains to be answered how these limiting factors are preferentially recruited to early origins. Here, w...

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Detalles Bibliográficos
Autores principales: Fang, Dingqiang, Lengronne, Armelle, Shi, Di, Forey, Romain, Skrzypczak, Magdalena, Ginalski, Krzysztof, Yan, Changhui, Wang, Xiaoke, Cao, Qinhong, Pasero, Philippe, Lou, Huiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795786/
https://www.ncbi.nlm.nih.gov/pubmed/29330352
http://dx.doi.org/10.1101/gad.306571.117