Cargando…
The RES complex is required for efficient transformation of the precatalytic B spliceosome into an activated B(act) complex
The precise function of the trimeric retention and splicing (RES) complex in pre-mRNA splicing remains unclear. Here we dissected the role of RES during the assembly and activation of yeast spliceosomes. The efficiency of pre-mRNA splicing was significantly lower in the absence of the RES protein Sn...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795787/ https://www.ncbi.nlm.nih.gov/pubmed/29330354 http://dx.doi.org/10.1101/gad.308163.117 |