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The RES complex is required for efficient transformation of the precatalytic B spliceosome into an activated B(act) complex

The precise function of the trimeric retention and splicing (RES) complex in pre-mRNA splicing remains unclear. Here we dissected the role of RES during the assembly and activation of yeast spliceosomes. The efficiency of pre-mRNA splicing was significantly lower in the absence of the RES protein Sn...

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Detalles Bibliográficos
Autores principales: Bao, Penghui, Will, Cindy L., Urlaub, Henning, Boon, Kum-Loong, Lührmann, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795787/
https://www.ncbi.nlm.nih.gov/pubmed/29330354
http://dx.doi.org/10.1101/gad.308163.117

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