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Fbxw7 regulates renal cell carcinoma migration and invasion via suppression of the epithelial-mesenchymal transition

F-box and WD repeat domain containing 7 (Fbxw7) is an F-box protein that belongs to the SKP1-CUL1-F-box protein E3 ligase complex and is responsible for transferring the ubiquitin molecule to the substrate, which results in its recognition and subsequent degradation by proteasomes. Furthermore, it c...

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Detalles Bibliográficos
Autores principales: He, Hongchao, Dai, Jun, Xu, Zhaoping, He, Wei, Wang, Xiaojing, Zhu, Yu, Wang, Haofei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795825/
https://www.ncbi.nlm.nih.gov/pubmed/29456733
http://dx.doi.org/10.3892/ol.2018.7744