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Fbxw7 regulates renal cell carcinoma migration and invasion via suppression of the epithelial-mesenchymal transition
F-box and WD repeat domain containing 7 (Fbxw7) is an F-box protein that belongs to the SKP1-CUL1-F-box protein E3 ligase complex and is responsible for transferring the ubiquitin molecule to the substrate, which results in its recognition and subsequent degradation by proteasomes. Furthermore, it c...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795825/ https://www.ncbi.nlm.nih.gov/pubmed/29456733 http://dx.doi.org/10.3892/ol.2018.7744 |