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Mesenchymal Stem Cell–Derived Small Extracellular Vesicles Promote Neuroprotection in Rodent Models of Glaucoma

PURPOSE: To investigate the benefit of bone marrow mesenchymal stem cell (BMSC)-derived small extracellular vesicles (sEV) as an intravitreal (ivit) therapy in two rat models of glaucoma and to determine and identify candidate miRNA involved in the mechanism. METHODS: sEV were isolated from human BM...

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Detalles Bibliográficos
Autores principales: Mead, Ben, Amaral, Juan, Tomarev, Stanislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795911/
https://www.ncbi.nlm.nih.gov/pubmed/29392316
http://dx.doi.org/10.1167/iovs.17-22855