Neuroprotective, Neurogenic, and Amyloid Beta Reducing Effect of a Novel Alpha 2-Adrenoblocker, Mesedin, on Astroglia and Neuronal Progenitors upon Hypoxia and Glutamate Exposure

Locus coeruleus-noradrenergic system dysfunction is known to contribute to the progression of Alzheimer’s disease (AD). Besides a variety of reports showing the involvement of norepinephrine and its receptor systems in cognition, amyloid β (Aβ) metabolism, neuroinflammation, and neurogenesis, little...

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Detalles Bibliográficos
Autores principales: Melkonyan, Magda M., Hunanyan, Lilit, Lourhmati, Ali, Layer, Nikolas, Beer-Hammer, Sandra, Yenkoyan, Konstantin, Schwab, Matthias, Danielyan, Lusine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795961/
https://www.ncbi.nlm.nih.gov/pubmed/29267189
http://dx.doi.org/10.3390/ijms19010009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795961/
https://www.ncbi.nlm.nih.gov/pubmed/29267189
http://dx.doi.org/10.3390/ijms19010009

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