Characterizing Metastatic HER2-Positive Gastric Cancer at the CDH1 Haplotype

The CDH1 gene, coding for the E-cadherin protein, is linked to gastric cancer (GC) susceptibility and tumor invasion. The human epidermal growth factor receptor 2 (HER2) is amplified and overexpressed in a portion of GC. HER2 is an established therapeutic target in metastatic GC (mGC). Trastuzumab,...

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Detalles Bibliográficos
Autores principales: Caggiari, Laura, Miolo, Gianmaria, Buonadonna, Angela, Basile, Debora, Santeufemia, Davide A., Cossu, Antonio, Palmieri, Giuseppe, De Zorzi, Mariangela, Fornasarig, Mara, Alessandrini, Lara, Canzonieri, Vincenzo, Lo Re, Giovanni, Puglisi, Fabio, Steffan, Agostino, Cannizzaro, Renato, De Re, Valli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795997/
https://www.ncbi.nlm.nih.gov/pubmed/29295527
http://dx.doi.org/10.3390/ijms19010047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795997/
https://www.ncbi.nlm.nih.gov/pubmed/29295527
http://dx.doi.org/10.3390/ijms19010047

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