Intracellular Renin Inhibits Mitochondrial Permeability Transition Pore via Activated Mitochondrial Extracellular Signal-Regulated Kinase (ERK) 1/2 during Ischemia in Diabetic Hearts

Although beneficial effects of non-secreting intracellular renin (ns-renin) against ischemia have been reported, the precise mechanism remains unclear. In this study, we investigated the roles of ns-renin and mitochondrial extracellular signal-related kinase (ERK) 1/2 on mitochondrial permeability t...

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Detalles Bibliográficos
Autores principales: Satoh, Terumori, Saotome, Masao, Katoh, Hideki, Nonaka, Daishi, Hasan, Prottoy, Hayashi, Hideharu, Maekawa, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796005/
https://www.ncbi.nlm.nih.gov/pubmed/29295576
http://dx.doi.org/10.3390/ijms19010055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796005/
https://www.ncbi.nlm.nih.gov/pubmed/29295576
http://dx.doi.org/10.3390/ijms19010055

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