High-Mobility Group Box 1 Mediates Fibroblast Activity via RAGE-MAPK and NF-κB Signaling in Keloid Scar Formation

Emerging studies have revealed the involvement of high-mobility group box 1 (HMGB1) in systemic fibrotic diseases, yet its role in the cutaneous scarring process has not yet been investigated. We hypothesized that HMGB1 may promote fibroblast activity to cause abnormal cutaneous scarring. In vitro w...

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Detalles Bibliográficos
Autores principales: Kim, Jihee, Park, Jong-Chul, Lee, Mi Hee, Yang, Chae Eun, Lee, Ju Hee, Lee, Won Jai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796026/
https://www.ncbi.nlm.nih.gov/pubmed/29283384
http://dx.doi.org/10.3390/ijms19010076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796026/
https://www.ncbi.nlm.nih.gov/pubmed/29283384
http://dx.doi.org/10.3390/ijms19010076

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