Identification of Two Novel Fibrinogen Bβ Chain Mutations in Two Slovak Families with Quantitative Fibrinogen Disorders

Congenital fibrinogen disorders are caused by mutations in one of the three fibrinogen genes that affect the synthesis, assembly, intracellular processing, stability or secretion of fibrinogen. Functional studies of mutant Bβ-chains revealed the importance of individual residues as well as three-dim...

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Detalles Bibliográficos
Autores principales: Simurda, Tomas, Zolkova, Jana, Snahnicanova, Zuzana, Loderer, Dusan, Skornova, Ingrid, Sokol, Juraj, Hudecek, Jan, Stasko, Jan, Lasabova, Zora, Kubisz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796050/
https://www.ncbi.nlm.nih.gov/pubmed/29286337
http://dx.doi.org/10.3390/ijms19010100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796050/
https://www.ncbi.nlm.nih.gov/pubmed/29286337
http://dx.doi.org/10.3390/ijms19010100

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