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Why Differentiation Therapy Sometimes Fails: Molecular Mechanisms of Resistance to Retinoids

Retinoids represent a popular group of differentiation inducers that are successfully used in oncology for treatment of acute promyelocytic leukemia in adults and of neuroblastoma in children. The therapeutic potential of retinoids is based on their key role in the regulation of cell differentiation...

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Detalles Bibliográficos
Autores principales: Chlapek, Petr, Slavikova, Viera, Mazanek, Pavel, Sterba, Jaroslav, Veselska, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796081/
https://www.ncbi.nlm.nih.gov/pubmed/29301374
http://dx.doi.org/10.3390/ijms19010132