ФC31 Integrase-Mediated Isolation and Characterization of Novel Safe Harbors for Transgene Expression in the Pig Genome

Programmable nucleases have allowed the rapid development of gene editing and transgenics, but the technology still suffers from the lack of predefined genetic loci for reliable transgene expression and maintenance. To address this issue, we used ФC31 integrase to navigate the porcine genome and ide...

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Detalles Bibliográficos
Autores principales: Bi, Yanzhen, Hua, Zaidong, Ren, Hongyan, Zhang, Liping, Xiao, Hongwei, Liu, Ximei, Hua, Wenjun, Mei, Shuqi, Molenaar, Adrian, Laible, Götz, Zheng, Xinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796098/
https://www.ncbi.nlm.nih.gov/pubmed/29300364
http://dx.doi.org/10.3390/ijms19010149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796098/
https://www.ncbi.nlm.nih.gov/pubmed/29300364
http://dx.doi.org/10.3390/ijms19010149

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