The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells

Neuroblastoma (NBL) originates from undifferentiated cells of the sympathetic nervous system. Chemotherapy is judged to be suitable for successful treatment of this disease. Here, the influence of histone deacetylase (HDAC) inhibitor valproate (VPA) combined with DNA-damaging chemotherapeutic, ellip...

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Detalles Bibliográficos
Autores principales: Cerna, Tereza, Hrabeta, Jan, Eckschlager, Tomas, Frei, Eva, Schmeiser, Heinz H., Arlt, Volker M., Stiborová, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796113/
https://www.ncbi.nlm.nih.gov/pubmed/29304031
http://dx.doi.org/10.3390/ijms19010164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796113/
https://www.ncbi.nlm.nih.gov/pubmed/29304031
http://dx.doi.org/10.3390/ijms19010164

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