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Introduction of Exogenous HSV-TK Suicide Gene Increases Safety of Keratinocyte-Derived Induced Pluripotent Stem Cells by Providing Genetic “Emergency Exit” Switch

Since their invention in 2006, induced Pluripotent Stem (iPS) cells remain a great promise for regenerative medicine circumventing the ethical issues linked to Embryonic Stem (ES) cell research. iPS cells can be generated in a patient-specific manner as an unlimited source of various cell types for...

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Detalles Bibliográficos
Autores principales: Sułkowski, Maciej, Konieczny, Paweł, Chlebanowska, Paula, Majka, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796146/
https://www.ncbi.nlm.nih.gov/pubmed/29315221
http://dx.doi.org/10.3390/ijms19010197