Antibacterial Evaluation and Virtual Screening of New Thiazolyl-Triazole Schiff Bases as Potential DNA-Gyrase Inhibitors

The global spread of bacterial resistance to drugs used in therapy requires new potent and safe antimicrobial agents. DNA gyrases represent important targets in drug discovery. Schiff bases, thiazole, and triazole derivatives are considered key scaffolds in medicinal chemistry. Fifteen thiazolyl-tri...

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Detalles Bibliográficos
Autores principales: Nastasă, Cristina, Vodnar, Dan C., Ionuţ, Ioana, Stana, Anca, Benedec, Daniela, Tamaian, Radu, Oniga, Ovidiu, Tiperciuc, Brînduşa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796171/
https://www.ncbi.nlm.nih.gov/pubmed/29324679
http://dx.doi.org/10.3390/ijms19010222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796171/
https://www.ncbi.nlm.nih.gov/pubmed/29324679
http://dx.doi.org/10.3390/ijms19010222

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