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Telomeric Repeat-Containing RNAs (TERRA) Decrease in Squamous Cell Carcinoma of the Head and Neck Is Associated with Worsened Clinical Outcome

Telomeres are transcribed into noncoding telomeric repeat-containing RNAs (TERRA), which are essential for telomere maintenance. Deregulation of TERRA transcription impairs telomere metabolism and a role in tumorigenesis has been proposed. Head and neck cancer (HNC) is one of the most frequent cance...

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Detalles Bibliográficos
Autores principales: Vitelli, Valerio, Falvo, Paolo, G. Nergadze, Solomon, Santagostino, Marco, Khoriauli, Lela, Pellanda, Paola, Bertino, Giulia, Occhini, Antonio, Benazzo, Marco, Morbini, Patrizia, Paulli, Marco, Porta, Camillo, Giulotto, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796220/
https://www.ncbi.nlm.nih.gov/pubmed/29342094
http://dx.doi.org/10.3390/ijms19010274