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Telomeres: Implications for Cancer Development

Telomeres facilitate the protection of natural ends of chromosomes from constitutive exposure to the DNA damage response (DDR). This is most likely achieved by a lariat structure that hides the linear telomeric DNA through protein-protein and protein-DNA interactions. The telomere shortening associa...

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Detalles Bibliográficos
Autores principales: Bernal, Aina, Tusell, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796239/
https://www.ncbi.nlm.nih.gov/pubmed/29351238
http://dx.doi.org/10.3390/ijms19010294