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Compatibility with Panax notoginseng and Rehmannia glutinosa Alleviates the Hepatotoxicity and Nephrotoxicity of Tripterygium wilfordii via Modulating the Pharmacokinetics of Triptolide

Tripterygium wilfordii (TW) and the representative active component triptolide show positive therapeutic effect on the autoimmune disorders and simultaneously ineluctable hepatotoxicity and nephrotoxicity. Combinational application of Panax notoginseng (PN) and Rehmannia glutinosa (RG) weakens the t...

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Detalles Bibliográficos
Autores principales: Zhang, Qichun, Li, Yiqun, Liu, Mengzhu, Duan, Jinao, Zhou, Xueping, Zhu, Huaxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796250/
https://www.ncbi.nlm.nih.gov/pubmed/29351251
http://dx.doi.org/10.3390/ijms19010305