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Deregulation of Frizzled Receptors in Hepatocellular Carcinoma

G protein-coupled receptors (GPCRs) have a substantial role in tumorigenesis and are described as a “cancer driver”. Aberrant expression or activation of GPCRs leads to the deregulation of downstream signaling pathways, thereby promoting cancer progression. In hepatocellular carcinoma (HCC), the Wnt...

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Detalles Bibliográficos
Autores principales: Chan, Kristy Kwan-Shuen, Lo, Regina Cheuk-Lam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796257/
https://www.ncbi.nlm.nih.gov/pubmed/29361730
http://dx.doi.org/10.3390/ijms19010313