Novel NAC-loaded poly(lactide-co-glycolide acid) nanoparticles for cataract treatment: preparation, characterization, evaluation of structure, cytotoxicity, and molecular docking studies

BACKGROUND: N-acetylcarnosine (NAC), a dipeptide with powerful antioxidant properties that is extensively used as a pharmaceutical prodrug for the treatment of cataract and acute gastric disease, was investigated by molecular dynamics with the GROMACS program in order to understand the solvent effec...

Descripción completa

Detalles Bibliográficos
Autores principales: Budama-Kilinc, Yasemin, Cakir-Koc, Rabia, Kecel-Gunduz, Serda, Kokcu, Yagmur, Bicak, Bilge, Mutlu, Hande, E. Ozel, Aysen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796282/
https://www.ncbi.nlm.nih.gov/pubmed/29404207
http://dx.doi.org/10.7717/peerj.4270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796282/
https://www.ncbi.nlm.nih.gov/pubmed/29404207
http://dx.doi.org/10.7717/peerj.4270

Ejemplares similares