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miR-302a-5p/367-3p-HMGA2 axis regulates malignant processes during endometrial cancer development

BACKGROUND: Metastasis is one of the main reasons for treatment failure in endometrial cancer. Notably, high mobility group AT-hook 2 (HMGA2) has been recognized as a driving factor of tumour metastasis. microRNAs (miRNAs) are powerful posttranscriptional regulators of HMGA2. METHODS: The binding si...

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Detalles Bibliográficos
Autores principales: Ma, Jian, Li, Da, Kong, Fan-Fei, Yang, Di, Yang, Hui, Ma, Xiao-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796297/
https://www.ncbi.nlm.nih.gov/pubmed/29391048
http://dx.doi.org/10.1186/s13046-018-0686-6