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The role of HFE genotype in macrophage phenotype

BACKGROUND: Iron regulation is essential for cellular energy production. Loss of cellular iron homeostasis has critical implications for both normal function and disease progression. The H63D variant of the HFE gene is the most common gene variant in Caucasians. The resulting mutant protein alters c...

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Detalles Bibliográficos
Autores principales: Nixon, Anne M., Neely, Elizabeth, Simpson, Ian A., Connor, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796391/
https://www.ncbi.nlm.nih.gov/pubmed/29391061
http://dx.doi.org/10.1186/s12974-018-1057-0