Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex

BACKGROUND: Mitochondria are the organelles responsible for energy metabolism and have a direct impact on neuronal function and survival. Mitochondrial abnormalities have been well characterized in Alzheimer Disease (AD). It is believed that mitochondrial fragmentation, due to impaired fission and f...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Sirui, Nandy, Priya, Wang, Wenzhang, Ma, Xiaopin, Hsia, Jeffrey, Wang, Chunyu, Wang, Zhenlian, Niu, Mengyue, Siedlak, Sandra L., Torres, Sandy, Fujioka, Hisashi, Xu, Ying, Lee, Hyoung-gon, Perry, George, Liu, Jun, Zhu, Xiongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796581/
https://www.ncbi.nlm.nih.gov/pubmed/29391029
http://dx.doi.org/10.1186/s13024-018-0238-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796581/
https://www.ncbi.nlm.nih.gov/pubmed/29391029
http://dx.doi.org/10.1186/s13024-018-0238-8

Ejemplares similares